Chao Xie

Researcher · Tsinghua University

Chao Xie谢超

Department of Psychological and Cognitive Sciences, Tsinghua University

Computational PsychiatryCognitive NeuroscienceNeuroimaging · fMRI/sMRINaturalistic BehaviorMachine Learning & AI

Research Vision

AI gives us a new opportunity to study the human brain — perhaps the most complex system in the universe. Using brain imaging and computational models, we seek to understand how human cognition works and develops across the lifespan.

By studying naturalistic behavior, we explore the complexity and creativity of human thought, while computational psychiatry connects these insights to mental health. In trying to understand the brain, we look not only to the stars above us, but also to the depths within ourselves.

Selected Publications

Recent Work

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Nat Med2023

A shared neural basis underlying psychiatric comorbidity

Xie C, Xiang ST, et al.

Nat Ment Health2026

Hierarchical Neurocognitive Model of Externalizing and Internalizing Comorbidity

Xie C, Xiang S, Zheng Y, et al.

Sci Adv2021

Neural Network Involving Medial Orbitofrontal Cortex and Dorsal Periaqueductal Gray Regulation in Human Alcohol Abuse

Jia T*, Xie C*, Banaschewski T, et al.

Research

Research Areas

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🧠

Neuroimaging in Psychiatric Disorders

Investigating neural correlates of psychiatric disorders using structural and functional MRI

📊

Computational Modeling of Cognition

Developing mathematical and computational models to understand cognitive processes and decision-making

⚕️

AI-Powered Clinical Tools

Developing artificial intelligence tools for diagnosis, prognosis, and treatment planning in psychiatry

🌐

Naturalistic Behavior Analysis

Understanding human behavior in real-world settings using wearable sensors and video analysis

Opportunities

Join Us

Open positions →
🧠

Brain Science

Study the human brain using neuroimaging techniques to understand neural mechanisms underlying cognition and behavior.

You Need:

sMRIfMRI
🤖

AI + Naturalistic Behavior

Apply artificial intelligence and large language models to analyze naturalistic human behavior and cognitive processes.

You Need:

AILLM
💚

Mental Health

Bridge neuroscience and clinical practice to understand mental disorders and develop computational models for psychiatry.

You Need:

PsychologyPsychiatryComputational Psychiatry

Recommended Background Knowledge

Brain Science

  • • Neuroimaging analysis (FSL, SPM, AFNI)
  • • Brain anatomy and connectivity
  • • Statistics and experimental design

AI + Behavior

  • • Machine learning / Deep learning
  • • Natural language processing
  • • Programming (Python, PyTorch)

Mental Health

  • • Psychopathology and diagnosis
  • • Clinical assessment methods
  • • Translational research

Interested in Collaboration or Joining the Lab?

We welcome motivated PhD students, postdocs, and research collaborators in computational neuroscience, psychiatry, and AI.